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The Efficacy and Safety of Pulp Regeneration Induced by SHED Polymerization

NCT05728346 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2023-08-28

No results posted yet for this study

Summary

Dental pulp necrosis is one of the most common pathological conditions that results in tooth loss. However, regeneration of functional dental pulp has proved difficult. Therefore, the investigators conduct a single-arm study to evaluate the efficacy and safety of pulp regeneration induced by SHED mixed with hyaluronic acid polymerization in patients with pulp necrosis of permanent teeth.

Conditions

  • Pulp Necroses

Interventions

DRUG

Allogeneic human pulp mesenchymal stem cells mixed with hyaluronic acid polymers

stem cells from human exfoliated deciduous teeth (SHED) mixed with hyaluronic acid polymers

Sponsors & Collaborators

  • Fifth Affiliated Hospital of Guangzhou Medical University

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2026-06-30
Completion
2026-09-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05728346 on ClinicalTrials.gov