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Fetal, Obstetrics and Reproduction Genomics

NCT05720169 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2023-09-14

No results posted yet for this study

Summary

The purpose of this study is to determine the impact of a clinical screening strategy and genomic analysis of the factors involved in Placental Dysfunction (Preeclampsia and IUGR) in women of advanced maternal age undergoing assisted reproduction techniques (ART), specifically, in vitro fertilization (IVF) and oocyte donation.

Conditions

  • Preeclampsia
  • Intrauterine Growth Restriction
  • Placental Disease

Interventions

DIAGNOSTIC_TEST

Doppler ultrasound

Doppler ultrasound at 13, 16, 20 and 26 weeks for assessment of uterine arteries according to ISUOG criteria.

DIAGNOSTIC_TEST

Blood sample

Blood sampling at 13, 16, 20, 26 weeks of gestation to determine the sFlt-1/PlGF ratio

DIAGNOSTIC_TEST

Blood sample

Blood sampling at week 13 for DNA extraction for genomic studies

DIAGNOSTIC_TEST

Doppler ultrasound

Fetal morphological ultrasound at 13, 16 and 20 weeks.

Sponsors & Collaborators

  • Hospitales Universitarios Virgen del Rocío

    collaborator OTHER

  • University of Seville

    collaborator OTHER

  • Clínicas Ginemed

    collaborator UNKNOWN

  • FIRST - Fetal, IVF and Reproduction Simulation Training Center

    collaborator UNKNOWN

  • Fundación Ginemed

    lead OTHER

Eligibility

Min Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2024-12-31
Completion
2024-12-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05720169 on ClinicalTrials.gov