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Gene Expression In Pregnancies Complicated by Preeclampsia

NCT00919360 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 125

Last updated 2015-10-21

No results posted yet for this study

Summary

The purpose of this study is to figure out some of the differences in bodily function between women who have preeclampsia and those who do not.

* This may eventually lead to an understanding of its cause. At this time, there is no known way to prevent preeclampsia, and the cause is not known.
* The only treatment is delivery of the baby, even if it is premature, in order to decrease the risk to the mother.

Conditions

Interventions

PROCEDURE

collection of maternal blood specimen prior to delivery

approximately 5 cc. of maternal blood will be drawn prior to delivery

PROCEDURE

collection of placental cord blood after delivery

approximately 5 cc. of fetal cord blood from the umbilical cord blood vessel will be collected after cord is clamped

PROCEDURE

collection of placental tissue

within 10 minutes of delivery, the placenta will be radially transected, and a full-thickness slice from the central region removed using sterile technique by scalpel.This will be placed into a pre-prepared container of RNA preservation medium.

PROCEDURE

collection of strip of decidua from uterine lining from cesarean section deliveries

A strip of decidua will be removed from the upper lip of uterine incision by the surgeon and placed in RNA preservation medium.

Sponsors & Collaborators

  • University of Rochester

    lead OTHER

Principal Investigators

  • Eva Pressman, MD · University of Rochester

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-06-30
Primary Completion
2015-07-31
Completion
2015-07-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00919360 on ClinicalTrials.gov