A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Liver Cancer
NCT05719480 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2023-02-09
Summary
The incidence of liver cancer in China shows a clear clinical path of hepatitis/fatty liver liver cirrhosis liver cancer. The dynamic changes of the internal environment on this pathway are important clues for early detection, diagnosis and even cure of liver cancer. The investigators carried out this study to investigate the changes of plasma and urine metabolites in different liver diseases during the occurrence and development of liver cancer.
Conditions
- Liver Cancer
- Liver Cirrhosis
- Fatty Liver
- Hepatitis
Interventions
- DIAGNOSTIC_TEST
-
Proteomics technology and liquid biopsy
using proteomics technology and liquid biopsy to investigate the changes of plasma and urine metabolites in different liver diseases during the development of liver cancer by collecting residual blood and urine from routine diagnosis and treatment or physical examination
Sponsors & Collaborators
-
Nanfang Hospital, Southern Medical University
lead OTHER
Principal Investigators
-
jian guan, MD · Nanfang Hospital, Southern Medical University
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-11-20
- Primary Completion
- 2025-11-20
- Completion
- 2025-12-20
Countries
- China
Study Locations
More Related Trials
-
The Surveillance of Hepatocellular Carcinoma
NCT05286099 ·Status: UNKNOWN
-
Diagnosis of Hepatic Tumors in Cirrhosis: Prospective Validation of the Noninvasive Diagnostic Criteria for Hepatocellular Carcinoma
NCT00842647 ·Status: UNKNOWN
-
Observational Study About Patients Diagnosed With NAFLD
NCT05625750 ·Status: RECRUITING
-
Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment
NCT01492127 ·Status: UNKNOWN ·Phase: NA
-
Establishment of Scoring Model for Early and Differential Diagnosis of Intrahepatic Cholangiocarcinoma
NCT05327907 ·Status: UNKNOWN
-
Early Screening of Hepatocellular Carcinoma in Cirrhotic Patients: a Prospective Study
NCT00629421 ·Status: COMPLETED
-
Diagnosis of Nodules ≤2 cm Based on US and CEUS Compared With Current Clinical Procedure
NCT05360420 ·Status: UNKNOWN ·Phase: NA
-
Dissection of the Molecular and Immunological Interaction in Patients With HCC of Viral and Non-viral Etiologies
NCT05613621 ·Status: ACTIVE_NOT_RECRUITING
-
The Role of Serum AKR1B10 in Early Warning of Hepatocellular Carcinoma in Cirrhosis Patients
NCT07147335 ·Status: RECRUITING
-
Study on the Quantitative Assessment of the Risk of Hepatocellular Carcinoma in Patients With Chronic Liver Disease Using Multi-parameter Magnetic Resonance Imaging
NCT06060769 ·Status: RECRUITING
-
Association of HsCAR with MAFLD and Liver Fibrosis: a Cross-sectional Study
NCT05974904 ·Status: RECRUITING
-
Study of Serum Tumor Markers of HBV Associated HCC
NCT05825196 ·Status: NOT_YET_RECRUITING
-
Dynamic Changes and Risk Factors of Fibrosis and Steatosis Progression in Nonalcoholic Fatty Liver Disease
NCT03635541 ·Status: UNKNOWN
-
Monitoring Changes in Hepatic Steatosis Using Continuous Controlled Attenuation Parameter
NCT06203548 ·Status: RECRUITING ·Phase: NA
-
Prospective Surveillance for Very Early Hepatocellular Carcinoma
NCT03588442 ·Status: UNKNOWN
-
Tumor Growth Factors in Hepatocellular Carcinoma
NCT00764140 ·Status: COMPLETED
-
Establishment of Precise Histological Evaluation Criteria for NASH Fibrosis Reversal
NCT06707129 ·Status: RECRUITING
-
Clinical Application of Quantitative Major Imaging Features of CEUS LI-RADS
NCT06590948 ·Status: RECRUITING
-
Characteristic and Survival Outcomes in Hepatocellular Carcinoma Patients: on Top of Viral Hepatitis Versus Combined Viral and Metabolic-Associated Steatotic Liver Disease
NCT06871930 ·Status: NOT_YET_RECRUITING
-
A Prospective Study of UCAD for Diagnosing Benign or Malignant Biliary Obstruction and Follow-up
NCT05237193 ·Status: UNKNOWN
-
To Evaluate the Efficacy and Safety of (18F-FCH) Comparing With (18F-FDG) for Detecting Hepatocellular Carcinoma
NCT02074202 ·Status: UNKNOWN ·Phase: PHASE3
-
Circulating Tumor Cell Detection in Hepatocellular Carcinoma
NCT05297955 ·Status: COMPLETED
-
Quantitative Diagnosis of Liver Fibrosis on Multiparametric MRI
NCT03176797 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Comprehensive Prognostic Model: The Study Introduces a Novel Prognostic Model That Incorporates a Wide Range of Clinical and Laboratory Variables, Providing a More Holistic Approach to Predicting Overall Survival in HCC Patients
NCT06550739 ·Status: COMPLETED
-
Combining Biomarkers (AFP, AFP-L3, and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma
NCT04414956 ·Status: RECRUITING ·Phase: NA