The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer

Summary

The goal of this clinical trial is to learn about the cause of dizziness and decline in walking ability in in older adults ≥65 years during chemotherapy treatment for colorectal cancer. Another goal is to investigate if a comprehensive geriatric assessment and three months' specialized physical group-based exercise three times/week can counteract muscle weakness, vertigo, instability, impaired walking balance, and neuropathy

Conditions

• Colorectal Cancer
• Oncologic Complications
• Comprehensive Geriatric Assessment
• Vestibular Rehabilitation
• Geriatric Oncology
• Sarcopenia
• Vertigo
• Cancer
• Rehabilitation
• Exercise
• Geriatric
• Elderly
• Frail
• Older Adults
• Chemotherapy
• Chemotherapy-induced Peripheral Neuropathy
• Resistance Training
• Balance Training
• Postural Stability
• Pragmatic Trial
• Personal Medicine
• Individualised

Interventions

OTHER

Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement

Vestibular rehabilitation, balance- and progressive resistance training for three months' three times/week and Comprehensive Geriatric Assessement including corresponding interventions

Sponsors & Collaborators

• Copenhagen University Hospital - Rigshospitalet, Department of Occupational Therapy and Physiotherapy

  collaborator UNKNOWN

• Copenhagen University Hospital at Herlev

  collaborator OTHER

• Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital

  collaborator UNKNOWN

• Odense University Hospital, Department of Geriatric Medicine

  collaborator UNKNOWN

• Copenhagen University Hospital - Amager and Hvidovre Hospital

  collaborator UNKNOWN

• Rigshospitalet, Denmark

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-02-20

Primary Completion

2027-05-01

Completion

2027-09-30

Countries

• Denmark

Study Locations