CT-based HVPG Assessment for Predicting the Prognosis of HCC With TACE (CHANCE-CHESS 2302)
NCT05704192 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 373
Last updated 2023-05-31
Summary
This study aims to evaluate the impact of non-invasive CT-based Hepatic Venous Pressure Gradient (HVPG) assessment on prognosis of hepatocellular carcinoma (HCC) patients treated with transarterial chemoembolization (TACE).
Conditions
- Hepatocellular Carcinoma
- Portal Hypertension
Interventions
- PROCEDURE
-
TACE ± Systemic therapy
TACE: conventional TACE (cTACE) or drug-eluting beads TACE (dTACE); Systemic therapy: programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1) inhibitors, vascular endothelial growth factor -tyrosine kinase inhibitor (VEGF-TKI)/bevacizumab, PD-1/PD-L1 inhibitors+VEGF-TKI/bevacizumab, radiotherapy or chemotherapy.
Sponsors & Collaborators
-
Zhongda Hospital
lead OTHER
Principal Investigators
-
Gao-Jun Teng · Zhongda hospital, Southeast university, Nanjing, China
-
Xiaolong Qi, M.D. · Zhongda Hospital, Medical School, Southeast University, Nanjing, China
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-04
- Primary Completion
- 2023-06-30
- Completion
- 2023-12-31
Countries
- China
Study Locations
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