Proseq Cancer: Genomic Profiling in Patients With Incurable Cancer in Search for Targeted Treatment
NCT05695638 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2024-01-31
Summary
Proseq Cancer is a precision medicine program based on in-house whole exome sequencing (WES) and RNA sequencing. The approved protocol allows for biobanking, registration of clinical and laboratory data, and sharing of genomic data with the purpose of research, while fulfilling the Danish General Data Protection Regulation (GDPR) requirements. Patients are recruited from the North Denmark Region.
Treatment can be offered on site if a targeted drug of a nationally approved indication is suggested by the national tumor board (NTB). If not, the patient may be treated in an available clinical protocol. If no approved drug or relevant protocol is available or feasible, treatment with a targeted drug used outside a clinical protocol is pursued.
Conditions
- Solid Tumor, Unspecified, Adult
- Haematological Malignancy
Sponsors & Collaborators
-
Morten Ladekarl
lead OTHER
Principal Investigators
-
Morten Ladekarl, MD, DMSCi · Department of Oncology, Aalborg University Hospital, Denmark
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-07-01
- Primary Completion
- 2030-05-31
- Completion
- 2035-05-31
Countries
- Denmark
Study Locations
More Related Trials
-
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
NCT03707574 ·Status: COMPLETED
-
Genomic Sequencing in Determining Treatment in Patients With Metastatic Cancer or Cancer That Cannot Be Removed by Surgery
NCT02566421 ·Status: TERMINATED ·Phase: NA
-
Analysis of Prostate Cancer Short-Term Cultures Using Molecular Cytogenetic Methods
NCT00022919 ·Status: COMPLETED
-
STRucturation of Transcript Analysis of Genes Involved in Hereditary Cancers
NCT06861621 ·Status: RECRUITING
-
PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine
NCT05697198 ·Status: COMPLETED
-
Feasibility Study of Genomic Sequencing to Find Potential Targets for Personalized Therapy
NCT01869218 ·Status: COMPLETED
-
Clinical Application of Genetic Sequencing of Early Gastric Cancer and Gastric Adenoma Patients
NCT04665687 ·Status: RECRUITING
-
Study of Tumor Samples in Patients Undergoing Treatment for Gastrointestinal Stromal Tumors on Clinical Trial ACOSOG-Z9001
NCT00954655 ·Status: COMPLETED
-
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
NCT05530759 ·Status: RECRUITING
-
Personalized Sequence for Thoracic, Esophageal, and H&N Cancer
NCT02299622 ·Status: UNKNOWN
-
Characterization of Human Cancers by Molecular Profiling of Patient Biospecimens
NCT02749838 ·Status: UNKNOWN
-
S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma
NCT00985699 ·Status: COMPLETED
-
Onco-Genomas Brasil: Mapping Breast and Prostate Cancer in the Brazilian Public Health System
NCT05306600 ·Status: RECRUITING
-
Feasibility Study of Genomic Profiling Methods and Timing in Tumor Samples
NCT01703585 ·Status: COMPLETED
-
Treatment Guided by Comprehensive Genome and Transcriptome Analysis Versus Standard of Care in Advanced Rare Cancers
NCT06855134 ·Status: RECRUITING
-
S9704-S0014-S0313A Studying Genes in Samples From Patients With Limited or Advanced Diffuse Large B-Cell Lymphoma
NCT01563861 ·Status: COMPLETED
-
Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection
NCT05585684 ·Status: RECRUITING
-
Mutational Oncology in Clinical Practice
NCT06020625 ·Status: RECRUITING ·Phase: NA
-
Theranostic Approach by Early Multigene Sequencing in Advanced Poor Prognosis Cancers
NCT06958224 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Strategic Targeting for Optimal Prevention of Cancer
NCT03897374 ·Status: RECRUITING
-
Prostate Tissue BioBank
NCT06659614 ·Status: RECRUITING
-
Whole-Exome Sequencing (WES) of Cancer Patients
NCT02127359 ·Status: COMPLETED
-
Circulating Free DNA Analysis in Gastrointestinal Cancer, Genitourinary Cancer, Rare Cancer
NCT02067754 ·Status: COMPLETED
-
UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations
NCT06895681 ·Status: NOT_YET_RECRUITING
-
Precision Medicine for Patients With Identified Actionable Mutations
NCT04111107 ·Status: TERMINATED ·Phase: PHASE2