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Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye

NCT05692739 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 116

Last updated 2026-03-05

No results posted yet for this study

Summary

This is a parallel randomized controlled trial for the treatment of dry eye disease. The main objective is to investigate the efficacy and safety of the use of insulin eye drops in the control of moderate-severe dry eye disease. Topical insulin drops will be compared to the current gold standard treatment, cyclosporin and placebo (artificial tears).

Conditions

Interventions

DRUG

Insulin

see arm description

DRUG

Cyclosporins

see arm description

DRUG

Artificial tears

see arm description

Sponsors & Collaborators

  • Barbara Burgos Blasco

    lead OTHER

Principal Investigators

  • Barbara Burgos Blasco, MD, PhD · Hospital Clinico San Carlos

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-19
Primary Completion
2025-11-05
Completion
2025-11-05

Countries

  • Spain

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05692739 on ClinicalTrials.gov