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Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.

NCT06939959 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 126

Last updated 2025-04-23

No results posted yet for this study

Summary

This is a parallel randomized controlled trial for the treatment of dry eye disease. The main objective is to investigate the efficacy and safety of the use of insulin eye drops in the control of moderate-severe dry eye disease. Topical insulin drops will be compared to artificial tears in improving the ocular surface interface in patients with dry eye disease over 1 year period.

Conditions

  • Dry Eye
  • Insulin Sensitivity

Interventions

DRUG

Artificial tear

commercially available artificial tears will be used consisting of same ingredients.

DRUG

insulin human

injection humulin will be used to make topical insulin drops

Sponsors & Collaborators

  • Khyber Teaching Hospital

    lead OTHER

Principal Investigators

  • Shafiq Tanvee, MBBS, FCPS · KHYBER TEACHING HOSPITAL PESHAWAR KPK PAKISTAN

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-14
Primary Completion
2026-01-20
Completion
2026-04-20

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06939959 on ClinicalTrials.gov