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Sleep Modulation as Antidepressant Randomized Trial

NCT05685771 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2024-07-26

No results posted yet for this study

Summary

The goal of this clinical trial is to learn about the effects of phase-targeted auditory stimulation in depressed patients and healthy controls.

The main questions it aims to answer are:

* Is auditory down-phase stimulation efficient in improving depression symptoms as compared to sham stimulation?
* Can mood and other outcomes be prospectively estimated by multi-parametric passive data?

Participants will perform auditory stimulation using a wearable device at home and provide data on their phone usage and activity.

Researchers will compare depressed patients and healthy participants to see if auditory down-phase stimulation effects them differently.

Conditions

Interventions

DEVICE

Phase-targeted auditory stimulation

Bursts of pink noise (50 ms) played during deep non-REM sleep at specific phases of sleep slow waves.

Sponsors & Collaborators

  • ETH Zurich

    collaborator OTHER

  • University of Zurich

    collaborator OTHER

  • Psychiatric University Hospital, Zurich

    collaborator OTHER

  • Giulia Da Poian

    lead OTHER

Principal Investigators

  • Giulia Da Poian, PhD · Sensory-Motor Systems Lab, IRIS, ETH Zurich

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2024-07-25
Completion
2024-07-25

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05685771 on ClinicalTrials.gov