WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma
NCT05678998 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2026-01-06
Summary
A first-in-human, Phase 1, open-label, multicenter study of WTX-330 administered as a monotherapy to patients with advanced or metastatic solid tumors or non-Hodgkin lymphoma.
Conditions
- Advanced or Metastatic Solid Tumors
- Non-Hodgkin Lymphoma
Interventions
- DRUG
-
WTX-330
Investigation Product
Sponsors & Collaborators
-
Werewolf Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-12-06
- Primary Completion
- 2024-12-23
- Completion
- 2025-02-05
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Study of ES002023 (Anti-CD39 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors
NCT05075564 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of XMT-1660 in Participants With Solid Tumors
NCT05377996 ·Status: RECRUITING ·Phase: PHASE1
-
A Study Explore WJB001 Capsules in Patients With Advanced Solid Tumors
NCT05773820 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
NCT06150664 ·Status: RECRUITING ·Phase: PHASE1
-
Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX51 in Patients With Solid Tumor or Lymphoma
NCT05788107 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
XTX202 in Patients With Advanced Solid Tumors
NCT05052268 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
NCT05873686 ·Status: RECRUITING ·Phase: PHASE1
-
A Study Evaluates the Safety, Pharmacokinetics and Efficacy of WX-0593 in Advanced Solid Tumor Patients
NCT03389815 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Phase 1, First in Human, Open-Label, Dose-Escalation Study of 609A
NCT03950297 ·Status: UNKNOWN ·Phase: PHASE1
-
DPTX3186 in Wnt Pathway Activated Solid Tumors
NCT07312903 ·Status: RECRUITING ·Phase: PHASE1
-
Phase 1 Study of BXQ-350 in Adult Patients With Advanced Solid Tumors
NCT02859857 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06307795 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of APX3330 in Patients With Advanced Solid Tumors
NCT03375086 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1, First in Human, Open-Label, Dose-Escalation Study of 609A in China
NCT03998345 ·Status: UNKNOWN ·Phase: NA
-
Safety and Pharmacologic Study of VTX-2337 in Patients With Advanced Cancer
NCT00688415 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of Bi-Weekly rBBX-01 in Patients With Solid Tumors
NCT00869388 ·Status: COMPLETED ·Phase: PHASE1
-
Study of PYX-106 in Solid Tumors
NCT05718557 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase I First in Human Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of WGI-0301 in Patients With Advanced Solid Tumors
NCT05267899 ·Status: UNKNOWN ·Phase: PHASE1
-
First in Human Study of UCT-03-008 in Participants With Advanced Solid Tumors
NCT05103046 ·Status: RECRUITING ·Phase: PHASE1
-
A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors
NCT05981703 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of HLX35 in Combination With HLX10 in Patients With Advanced or Metastatic Solid Tumors
NCT05442996 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase I/II Dose-escalation Study to Investigate Safety and Pharmacokinetics/ Pharmacodynamics of WX-554 in Patients With Solid Tumours
NCT01581060 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors
NCT02298387 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors
NCT01966445 ·Status: COMPLETED ·Phase: PHASE1
-
A First-in-human of Multiplle Doses of BB-1709 in Subjects With Locally Advanced/Metastatic Solid Tumors
NCT06241898 ·Status: RECRUITING ·Phase: PHASE1