Study of PYX-106 in Solid Tumors
NCT05718557 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 47
Last updated 2025-08-03
Summary
The primary objective of this study is to determine the recommended dose(s) of PYX-106 in participants with relapsed/refractory solid tumors.
Conditions
Interventions
- DRUG
-
PYX-106
Intravenous (IV) infusion
Sponsors & Collaborators
-
Pyxis Oncology, Inc
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-23
- Primary Completion
- 2026-05-31
- Completion
- 2026-05-31
- FDA Drug
- Yes
Countries
- United States
- Belgium
- Spain
Study Locations
More Related Trials
-
A Study Of PF-06647263 In Patients With Advanced Solid Tumors
NCT02078752 ·Status: TERMINATED ·Phase: PHASE1
-
A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies
NCT05753722 ·Status: RECRUITING ·Phase: PHASE1
-
Ph. 1, Evaluation of Safety, Tolerability, PK, Anti-tumor Activity of STP707 IV in Subjects With Solid Tumors
NCT05037149 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors
NCT05159700 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06307795 ·Status: RECRUITING ·Phase: PHASE1
-
Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.
NCT03891953 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Study of RXDX-105, Potent RET Inhibitor in Patients With Advanced Lung Cancer and Other Solid Tumors
NCT01877811 ·Status: COMPLETED ·Phase: PHASE1
-
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
NCT05735080 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of GDC-0941 in Participants With Locally Advanced or Metastatic Solid Tumors for Which Standard Therapy Either Does Not Exist or Has Proven Ineffective or Intolerable
NCT00876109 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors
NCT06431594 ·Status: RECRUITING ·Phase: PHASE1
-
Open Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Subjects With Advanced/Relapsed Solid Tumors
NCT02307240 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I/II Dose-escalation Study to Investigate Safety and Pharmacokinetics/ Pharmacodynamics of WX-554 in Patients With Solid Tumours
NCT01581060 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors
NCT06190886 ·Status: RECRUITING ·Phase: PHASE1
-
BMS-247550 in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy
NCT00004927 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors
NCT03762447 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies
NCT02571036 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of PQR309
NCT01940133 ·Status: COMPLETED ·Phase: PHASE1
-
Oral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors
NCT03454243 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors
NCT02009449 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
NCT06993844 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study of PKI-179 Administered Orally to Subjects With Solid Tumors
NCT00997360 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies
NCT00441337 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors
NCT01804530 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors
NCT05109975 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors
NCT05142592 ·Status: RECRUITING ·Phase: PHASE1/PHASE2