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Bacterial Metallophores in the Diagnosis of Acute Pyelonephritis

NCT05674032 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2023-01-06

No results posted yet for this study

Summary

The project aims to investigate bacterial metallophores as potential diagnostic markers of acute pyelonephritis and complicated urinary tract infections. These secondary metabolites are excreted by pathogenic microorganims in the course of infection for the uptake of iron and other metallic ions from the host. They are species-specific and can be detected in body fluids (including urine) by mass spectrometry. The potential contribution of this project is a culture-independent method for the diagnosis of the causative microbiological agent.

Conditions

  • Acute Pyelonephritis
  • Complicated Urinary Tract Infection

Sponsors & Collaborators

  • Czech Academy of Sciences

    collaborator OTHER

  • Thomayer University Hospital

    lead OTHER

Principal Investigators

  • Jan Hrbacek, PhD. · Thomayer University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-06-24
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05674032 on ClinicalTrials.gov