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The Effects of Combined Gum-chewing and Parenteral Metoclopramide on Post-operative Ileus

NCT05669781 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 105

Last updated 2023-01-03

No results posted yet for this study

Summary

A delay in the return of bowel function is a common occurrence after abdominal surgeries.1 The goal of this study was to test the effect of the combined use of chewing a gum and administering metoclopramide intravenously on the duration of this natural delay in the return of bowel function after abdominal surgeries. Patients were grouped into four: the first group received both gum and metoclopramide; the second group received only gum; the third group received only metoclopramide, while the fourth group (the control group) received sterile water for injection. The groups were compared for the time taken for bowel function to return and the duration of hospital stay.

Conditions

  • Ileus Postoperative

Interventions

DRUG

Metoclopramide 10mg

Intravenous metoclopramide 10mg 8hourly for the first 72hours post-operatively

COMBINATION_PRODUCT

Gum and metoclopramide

Intravenous metoclopramide 10mg 8hourly for the first 72hours post-operatively and one stick of sugar-free gum (over 15minutes) 8 hourly till either the first flatus or feces was passed

OTHER

Gum

One stick of sugar-free gum (over 15minutes) 8 hourly till either the first flatus or feces was passed

OTHER

Control

10ml of sterile water intravenously 8hourly for the first 72hours post-operatively

Sponsors & Collaborators

  • Ikechukwu Bartholomew Ulasi

    lead OTHER

Principal Investigators

  • Ikechukwu B. Ulasi · University College Hospital, Ibadan

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
FACTORIAL

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2019-09-30
Completion
2019-09-30

Countries

  • Nigeria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05669781 on ClinicalTrials.gov