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Accelerated Aging in Newborns and Adults With Congenital Heart Disease

NCT05667870 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1200

Last updated 2023-06-15

No results posted yet for this study

Summary

Many childhood-onset diseases used to be lethal. Improved life expectancy yield that most patients can survive into adulthood, to date. However, survivors of childhood-onset diseases often develop morbidities that suggest accelerated aging. Indeed, age-related conditions are observed sooner and more frequently in people with childhood-onset diseases. Congenital heart disease (CHD) is a typical example of a childhood-onset disease and is the most common birth defect, comprising a spectrum of mild, moderate and complex heart defects. Recent studies showed that age-related morbidities occur more often and at an earlier age in these patients. The overall goal of this project is to quantify and understand disparities in chronological and biological age over the lifespan in CHD patients.

Conditions

  • Heart Defects, Congenital

Sponsors & Collaborators

  • University Hospital, Ghent

    collaborator OTHER

  • Hasselt University

    collaborator OTHER

  • KU Leuven

    lead OTHER

Principal Investigators

  • Philip Moons, Prof. PhD · Professor in Healthcare Sciences

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-20
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05667870 on ClinicalTrials.gov