Orexin-A Levels in Insomnia Patients
NCT05664295 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2023-03-15
Summary
In the pathophysiology of insomnia, the increase of the orexin-A (OXA) peptide released from orexin neurons in the lateral hypothalamus plays an important role. Orexins takes part at the emergence of anesthesia. In the literature, investigators could not attain any studies about the arousal of insomnia patients from anesthesia. In this study, the effect of this peptide on the emergence process from anesthesia was investigated by comparing plasma OXA levels before and after anesthesia in insomnia patients.
Conditions
- Insomnia
- Anesthesia
Interventions
- DIAGNOSTIC_TEST
-
Jenkins Sleep Disorders scale and Epworth Sleepiness scale
Jenkins Sleep Disorders scale and Epworth Sleepiness scale
Sponsors & Collaborators
-
Muğla Sıtkı Koçman University
lead OTHER
Principal Investigators
-
melike Korkmaz Toker · Mugla Sıtkı Kocman University Department of Anesthesiology and reanimation
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-12-30
- Primary Completion
- 2023-01-30
- Completion
- 2023-02-10
Countries
- Turkey (Türkiye)
Study Locations
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