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Porphyromonas Gingivalis and Severity of Fibrosis in Patients With Non-alcoholic Fatty Liver Disease

NCT05654129 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 182

Last updated 2022-12-16

No results posted yet for this study

Summary

Many studies suggest that Porphyromonas gingivalis, a virulent periodontopathogenic bacterium, is associated with many systemic diseases such as cardiovascular diseases. In addition, a recent study showed the impact of Porphyromonas gingivalis on Non-Alcoholic Steatosis Liver Disease (NASH). It would be responsible for aggravation of non-alcoholic fatty liver disease (NAFLD) by stimulating inflammation in the damaged liver tissue.

Conditions

  • Non-Alcoholic Fatty Liver Disease

Interventions

OTHER

saliva samples

saliva samples (non-invasive, in the sites evaluated during the partial survey) will be perform by one of the investigators .

OTHER

medical questionnaire

a complete medical questionnaire will be carried out (general, lifestyle and quality of life) will be perform by one of the investigators .

Sponsors & Collaborators

  • University Hospital, Toulouse

    lead OTHER

Principal Investigators

  • Vincent BLASCO-BAQUE · University Hospital, Toulouse

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-12-05
Primary Completion
2022-12-05
Completion
2023-12-05

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05654129 on ClinicalTrials.gov