Project CADENCE (CAncer Detected Early caN be CurEd)
NCT05633342 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 15000
Last updated 2023-03-20
Summary
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be dysregulated during disease progression. Combining the power of multi-omic cancer biomarkers, the investigators hypothesize that the sensitivity and specificity of MiRXES MCST can be significantly improved compared to existing multi-cancer diagnostic tests.
In this study, the investigators propose to develop and validate blood-based, multi-cancer screening tests through a multi-omics approach.
Conditions
- Thoracic Cancer
- Ovarian Cancer
- Liver Cancer
- Prostate Cancer
- Gastric Cancer
- Colorectal Cancer
- Breast Cancer
- Esophageal Cancer
- Pancreatic Cancer
Sponsors & Collaborators
-
MiRXES Pte Ltd
lead INDUSTRY
Principal Investigators
-
Cheng He, PhD · MiRXES Pte Ltd
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-07-07
- Primary Completion
- 2024-12-31
- Completion
- 2025-05-31
Countries
- Singapore
Study Locations
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