PrEP Optimization Among Women to Enhance Retention and Uptake

Summary

Black women experience one of the highest incidences of HIV among all subpopulations in the United States, but pre-exposure prophylaxis (PrEP) use among Black cisgender women is very limited. The investigators will implement four strategies (provider training, patient education, EMR optimization, and PrEP navigation) at 12 community health clinics in the Midwest and South. The investigators predict that PrEP use and other related outcomes will improve for participants after the intervention period.

Conditions

• PrEP Uptake

Interventions

BEHAVIORAL

PrEP Education

Education for participants regarding PrEP

BEHAVIORAL

Provider training

Training for medical providers at CHCs about how to identify participants eligible for PrEP, how to perform behavioral risk assessment and discussion of PrEP, and how to prescribe PrEP and monitor PrEP

OTHER

EMR Optimization

EMR modifications to enhance PrEP care continuum outcomes including HIV risk assessment, identification of participants eligible for PrEP, provision of PrEP education, clinical decision support tools for prescription of PrEP, and tracking of PrEP care continuum outcomes using an electronic population health management tool

OTHER

PrEP Navigation

Use of CHC staff members to assist participants with obtaining PrEP and attending PrEP care appointments

OTHER

Provider Audit and Feedback

Audit of provider rates of PrEP prescription and persistence among participants and regular provision of feedback to providers with their performance on these PrEP measures

Sponsors & Collaborators

• AllianceChicago

  collaborator OTHER

• Howard Brown Health Center

  collaborator OTHER

• Ann & Robert H Lurie Children's Hospital of Chicago

  collaborator OTHER

• Northwestern University

  collaborator OTHER

• Rush University

  collaborator OTHER

• University of Chicago

  lead OTHER

Principal Investigators

• Jessica Ridgway, MD, MS · University of Chicago

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-08-10

Primary Completion

2026-04-30

Completion

2026-06-30

Countries

• United States

Study Locations