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Non-invasive MRD Assessment in Multiple Myeloma

NCT05625971 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 36

Last updated 2026-01-07

No results posted yet for this study

Summary

The purpose of this study is to investigate the sensitivity and accuracy of non-invasive MRD assessment using liquid biopsy (blood draw) and functional imaging (whole body MRI) in participants with new diagnosed and previously treated multiple myeloma. The long-term goal of this study is to investigate whether non-invasive methods for MRD assessment can replace bone marrow aspiration and biopsy in a substantial percentage of participants with multiple myeloma.

Conditions

Interventions

OTHER

MRD Assessment

MRD assessment includes liquid biopsy and functional imaging. Liquid biopsy will be performed by the Adaptive ClonoSEQ® assay in peripheral blood. Functional imaging will be performed by whole body diffusion-weighted magnetic resonance imaging (WB-DWI).

Sponsors & Collaborators

  • Hope Foundation

    collaborator OTHER

  • Rajshekhar Chakraborty, MD

    lead OTHER

Principal Investigators

  • Chakraborty Chakraborty, MD · Columbia University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-14
Primary Completion
2025-12-15
Completion
2025-12-15

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05625971 on ClinicalTrials.gov