Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
NCT05621837 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2025-05-02
Summary
The Serpentine (Stratify cancER PatiENTs by ImmuNosupprEssion) project, represents the most consistent effort so far attempted to translate MDSC into clinical practise by producing an off-the-shelf compliant assay for quantifying these cells in peripheral blood.
Conditions
- Melanoma
- Breast Cancer
- Renal Cell Carcinoma
- Urinary Bladder Cancer
- Squamous Cell Carcinoma of Head and Neck
- Small Cell Carcinoma
- NSCLC
Interventions
- OTHER
-
MDSC quantification
Blood sample will be collected at baseline and during therapy, and, optionally, in case of disease progression (PD).
Sponsors & Collaborators
-
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
lead OTHER
Principal Investigators
-
Licia Rivoltini · Fondazione IRCCS Istituto Nazionale Tumori - Milan
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-03-10
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Italy
Study Locations
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