Systematic Investigation of Blacks With Stroke - GENOMICS

Summary

The overall goal of SIBS-GENOMICS is to utilize the best available contextual data on stroke in Africa to develop \& validate stroke risk estimation models, translate the best model into a mobile phone app and conduct a randomized control trial of the app with a co-created motivational education video, to determine their effectiveness for improvement of stroke risk factor awareness and global risk reduction among Africans.

Conditions

• Hypertension
• Adult
• Dyslipidemias
• Physical Inactivity
• Diabetes
• Alcohol Consumption

Interventions

DEVICE

Riskometer Application

The intervention group participants at baseline will be assessed by installing a riskometer app on their mobile phones to calculate their global stroke risk score. They will be shown their risk scores and the specific risk factors identified through the screening. They will be counselled and supported to manage their risk factors through lifestyle changes and visit their healthcare provider for appropriate care.

BEHAVIORAL

Routine Clinic Therapy

After their assessment by the blinded adjudicator, the controls will visit the study doctor to obtain the routine clinic therapy and then will be allowed to go home.

Sponsors & Collaborators

• Medical University of South Carolina

  collaborator OTHER

• University of Ibadan

  collaborator OTHER

• Federal Medical Centre, Abeokuta

  collaborator UNKNOWN

• Ahmadu Bello University Teaching Hospital

  collaborator OTHER

• Bayero University Kano, Nigeria

  collaborator OTHER

• Kwame Nkrumah University of Science and Technology

  collaborator OTHER

• Korle-Bu Teaching Hospital, Accra, Ghana

  collaborator OTHER

• University of Alabama at Birmingham

  collaborator OTHER

• University of Washington

  collaborator OTHER

• University College Hospital, Ibadan

  lead OTHER

Principal Investigators

• Mayowa O. Owolabi, MD · College of Medicine University of Ibadan

• Bruce Ovbiagele, MD · University of California, San Francisco

• Fred S. Sarfo, PhD · Kwame Nkrumah University of Science & Technology (KNUST)

• Benjamin S. Aribisala, PhD · Lagos State University, (LASU)

• Michelle Nichols, PhD · Medical University of South Carolina

• Oyedunni S. Arulogun, PhD · University of Ibadan

• Carolyn Jenkins, PhD · Medical University of South Carolina

• Bukola Ajala, PhD · University of Ibadan

• Onoja M. Akpa, PhD · University of Ibadan

• Odun J. Akinyemi, PhD · University of Ibadan

• Rufus A. Akinyemi, PhD · University of Ibadan

• Reginald O. Obiako, PhD · Ahmadu Bello University Teaching Hospital, (ABUTH) Zaria

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-08-20

Primary Completion

2022-11-06

Completion

2022-12-15

Countries

• Ghana
• Nigeria

Study Locations