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Natural History of PRPF31 Mutation-Associated Retinal Dystrophy

NCT05573984 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2026-04-13

No results posted yet for this study

Summary

The purpose of this study is to characterize the natural history through temporal systemic evaluation of subjects identified with PRPF31 mutation-associated retinal dystrophy, also called retinitis pigmentosa type 11, or RP11.

Assessments will be completed to measure and evaluate structural and functional visual changes including those impacting patient quality of life associated with this inherited retinal condition and observing how these changes evolve over time.

Conditions

  • Retinitis Pigmentosa
  • Eye Diseases, Hereditary
  • Retinal Dystrophies
  • Retinal Dystrophy Rod
  • Retinal Dystrophy Rod Progressive

Sponsors & Collaborators

  • PYC Therapeutics

    lead INDUSTRY

Principal Investigators

  • Sreenivasu Mudumba, PhD · PYC Therapeutics

Eligibility

Min Age
10 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-07-07
Primary Completion
2026-09-09
Completion
2026-11-01

Countries

  • United States
  • Australia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05573984 on ClinicalTrials.gov