Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT
NCT02575430 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 59
Last updated 2016-04-29
Summary
To evaluate the natural history of visual function in subjects with IRD phenotypically diagnosed as Leber congenital amaurosis (LCA) or retinitis pigmentosa (RP) caused by RPE65 or LRAT gene mutations.
Conditions
- Leber Congenital Amaurosis (LCA)
- Retinitis Pigmentosa (RP)
Interventions
- OTHER
-
No treatment: retrospective chart review
Sponsors & Collaborators
-
QLT Inc.
lead INDUSTRY
Principal Investigators
-
David Saperstein, MD · QLT Inc.
Eligibility
- Min Age
- 8 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-12-31
- Primary Completion
- 2016-03-31
- Completion
- 2016-03-31
Countries
- United States
- Canada
- Denmark
- Germany
- Netherlands
- Switzerland
- United Kingdom
Study Locations
More Related Trials
-
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases
NCT02309866 ·Status: UNKNOWN
-
An Expanded Clinical Study Evaluating the AAV2-RPE65 Gene Therapy(LX101) in Patients With LCA
NCT06024057 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Autosomal Dominant Retinitis Pigmentosa: Prevalence of Known Genes Identification of New Loci / Genes
NCT01235624 ·Status: COMPLETED ·Phase: NA
-
Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa
NCT00065455 ·Status: COMPLETED ·Phase: PHASE1
-
CNGB1 and Allied Disorders
NCT04639635 ·Status: SUSPENDED
-
Gyrate Atrophy Ocular and Systemic Study
NCT05312736 ·Status: ACTIVE_NOT_RECRUITING
-
Single Ascending Dose Study in Participants With LCA10
NCT03872479 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Observational Natural History Study of Autosomal Dominant Retinitis Pigmentosa (adRP)
NCT02926092 ·Status: TERMINATED
-
Natural History, Pathogenesis, and Outcome of Ocular Disorders
NCT02821767 ·Status: RECRUITING
-
Structural and Functional Characterization of Rare Ocular Diseases
NCT05258032 ·Status: RECRUITING
-
Rod and Cone Mediated Function in Retinal Disease
NCT02617966 ·Status: RECRUITING
-
Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa
NCT06323772 ·Status: ACTIVE_NOT_RECRUITING
-
LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study
NCT06217588 ·Status: RECRUITING
-
Natural History of Eye Diseases Related to ABCA4 Mutations
NCT01736293 ·Status: ACTIVE_NOT_RECRUITING
-
Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.
NCT03990727 ·Status: UNKNOWN
-
Study of Nutritional Supplementation in Patients With Unilateral Wet AMD
NCT04756310 ·Status: COMPLETED ·Phase: NA
-
Investigation of the Genetic and Environmental Determinants of MP Including Response to Supplementation
NCT01778231 ·Status: COMPLETED ·Phase: NA
-
Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.
NCT02162953 ·Status: COMPLETED
-
Effects of Lutein in Retinitis Pigmentosa
NCT00029289 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety Study in Retinal Transplantation for Dry Age Related Macular Degeneration.
NCT00346060 ·Status: COMPLETED ·Phase: PHASE2
-
The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study
NCT05045703 ·Status: WITHDRAWN ·Phase: NA
-
Genetic Determinant of Foveolar Hypoplasia in Parents of Albinos Children
NCT03959605 ·Status: COMPLETED
-
DHA and X-Linked Retinitis Pigmentosa
NCT00100230 ·Status: COMPLETED ·Phase: PHASE2
-
MPOD in Macular Teleangiectasia Following Supplementation of Lutein and Zeaxanthin
NCT00568828 ·Status: UNKNOWN
-
Cone Rescue in Retinitis Pigmentosa by the Treatment of Lycium Barbarum
NCT02244996 ·Status: COMPLETED ·Phase: NA