Oxidative Stress in the Patient With Peroperative Analgesia by Intravenous Lidocaine
NCT05562141 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2024-01-17
Summary
Depending on the anesthesiologist's habits, injection or not of a 1.5 mg/kg bolus of lidocaine at induction of anesthesia followed by a continuous infusion of 1.5 mg/kg/h.
Additional blood sample at 3 different times without additional puncture compared to usual management: 1) during the placement of the venous line before induction (Reactive Oxygen Species), 2) 1h after the end of induction at the time of blood gas to adapt ventilation (Reactive Oxygen Species), 3) at 24h of the beginning of the intervention (Reactive Oxygen Species and antioxidant molecular profile).
Conditions
- Oxidative Stress
- Analgesia
Interventions
- BIOLOGICAL
-
Blood sample
Blood sample before induction, 1h after induction and 24h after the start of procedure
Sponsors & Collaborators
-
University Hospital, Tours
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-11-22
- Primary Completion
- 2023-07-17
- Completion
- 2023-07-18
Countries
- France
Study Locations
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