Oxidative Stress in the Patient With Peroperative Analgesia by Intravenous Lidocaine

NCT05562141 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2024-01-17

No results posted yet for this study

Summary

Depending on the anesthesiologist's habits, injection or not of a 1.5 mg/kg bolus of lidocaine at induction of anesthesia followed by a continuous infusion of 1.5 mg/kg/h.

Additional blood sample at 3 different times without additional puncture compared to usual management: 1) during the placement of the venous line before induction (Reactive Oxygen Species), 2) 1h after the end of induction at the time of blood gas to adapt ventilation (Reactive Oxygen Species), 3) at 24h of the beginning of the intervention (Reactive Oxygen Species and antioxidant molecular profile).

Conditions

  • Oxidative Stress
  • Analgesia

Interventions

BIOLOGICAL

Blood sample

Blood sample before induction, 1h after induction and 24h after the start of procedure

Sponsors & Collaborators

  • University Hospital, Tours

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-22
Primary Completion
2023-07-17
Completion
2023-07-18

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05562141 on ClinicalTrials.gov