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Understanding Pain Mechanisms in Knee Osteoarthritis

NCT05561010 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2022-09-30

No results posted yet for this study

Summary

UP-KNEE study is a feasibility, double-blind, placebo-controlled randomised parallel study in participants with radiographically defined knee OA, and with self-reported chronic knee pain.

Conditions

Interventions

DRUG

Intra-articular injection of bupivacaine in the knee joint

25 participants will be allocated to the bupivacaine arm.

DRUG

Intra-articular injection of placebo in the knee joint

25 participants will be allocated to the placebo arm.

Sponsors & Collaborators

  • University of Nottingham

    collaborator OTHER

  • Versus Arthritis

    collaborator OTHER

  • Aalborg University

    collaborator OTHER

  • Nottingham University Hospitals NHS Trust

    lead OTHER

Principal Investigators

  • Professor Brigitte Scammell · University of Nottingham

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-31
Primary Completion
2023-03-31
Completion
2023-03-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05561010 on ClinicalTrials.gov