Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee
NCT00372801 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2008-10-16
Summary
To demonstrate that new drugs work, many complex multidose studies are often required. The intent of this study is to use Ibuprofen as an example of a marketed pain relief drug to validate a simpler single dose model for future assessment of new pain drugs.
Conditions
Interventions
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-08-31
Countries
- Australia
More Related Trials
-
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (Europe)
NCT00630929 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (United States)
NCT00620867 ·Status: COMPLETED ·Phase: PHASE4
-
A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis
NCT01343303 ·Status: COMPLETED ·Phase: PHASE1
-
Acute Osteoarthritis Experimental Model Study.
NCT01231490 ·Status: COMPLETED ·Phase: PHASE2
-
Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
NCT00542555 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee
NCT00878501 ·Status: TERMINATED ·Phase: PHASE2
-
A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee
NCT00265304 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate Efficacy and Safety of X0002 in Treatment of Knee Osteoarthritis
NCT03691818 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the Knee
NCT00933582 ·Status: COMPLETED ·Phase: PHASE1
-
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
NCT00689273 ·Status: COMPLETED ·Phase: PHASE2
-
An Investigational Drug in Patients With Osteoarthritis (0663-073)
NCT00092755 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Celecoxib Versus Placebo in the Treatment of Patients With Osteoarthritis of the Knee Who Were Unresponsive to Naproxen and Ibuprofen
NCT00640627 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee
NCT01147458 ·Status: TERMINATED ·Phase: PHASE2
-
Safety, Tolerability and Pharmacokinetics of SAR113945 in Japanese Patients With Knee Osteoarthritis
NCT01511549 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Glucosamine or Ibuprofen Combined With Physical Training in Patients With Knee-Osteoarthritis
NCT00833157 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part II
NCT01598415 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Naproxen to Evaluate Various Methods of Measuring Analgesic Effect in Osteoarthritis Pain of the Knee
NCT01557816 ·Status: UNKNOWN ·Phase: NA
-
A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee
NCT01529671 ·Status: COMPLETED ·Phase: PHASE1
-
The Effect and Safety of Anti-inflammatories and Dextrose Prolotherapy Injections in Treating Knee Osteoarthritis
NCT06911359 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee
NCT02611466 ·Status: COMPLETED ·Phase: PHASE2
-
Osteoarthritis Topical Treatment
NCT01496326 ·Status: COMPLETED ·Phase: PHASE2
-
Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee
NCT01688934 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
NCT00504127 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Celecoxib vs Placebo to Prevent Pain in a Paced Walk
NCT00194090 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
NCT00296569 ·Status: COMPLETED ·Phase: PHASE2