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Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors

NCT05558384 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2025-02-24

No results posted yet for this study

Summary

This is a pilot feasibility study of an investigation of the influence of excess adiposity on cardiorespiratory fitness (CRF), insulin-like growth factor-1 (IGF-1), and metabolic responses to a standardized aerobic exercise program in cancer survivors. This investigation attempts to isolate the influence of adiposity on these responses. We will enroll overweight, obese, and normal weight cancer survivors with a primary diagnosis of breast, prostate, or colorectal cancer who have completed all cancer-related treatment. Participants will engage in a 15-week aerobic exercise intervention with pre- and post-intervention assessments.

Conditions

  • Cancer
  • Overweight and Obesity

Interventions

BEHAVIORAL

Aerobic Exercise

A 15-week standardized aerobic exercise intervention. * Frequency: 5 days/wk (2 supervised) * Intensity: 50-59% heart rate reserve * Time: 40 min/session (ramp up from 25-40 during first 4 weeks) * Type: Aerobic exercise (e.g. treadmill, walking/jogging, cycling, elliptical)

Sponsors & Collaborators

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • Ryan Marker · University of Colorado, Denver

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
21 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-22
Primary Completion
2024-10-01
Completion
2024-10-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05558384 on ClinicalTrials.gov