Beta-blockade With Landiolol in Out-of-hospital Cardiac Arrest
NCT05554978 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2023-03-17
Summary
This study investigates the efficacy of landiolol versus placebo in patients with out-of-hospital cardiac arrest (OHCA) and refractory ventricular fibrillation (electrical storm).
Conditions
- Cardiac Arrest
Interventions
- DRUG
-
Landiolol
patient receives landiolol in addition to standard-of-care
- DRUG
-
Sodium Chloride (NaCl) 0.9%
Placebo
Sponsors & Collaborators
-
Medical University of Vienna
lead OTHER
Principal Investigators
-
Michael M Holzer, MD · Medical University of Vienna
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-03-03
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
Countries
- Austria
Study Locations
More Related Trials
-
Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Response
NCT03715556 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison of High Versus Escalating Shocks in Cardioverting Atrial Fibrillation
NCT02923414 ·Status: COMPLETED ·Phase: NA
-
Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia
NCT01401647 ·Status: COMPLETED ·Phase: PHASE3
-
AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"
NCT00139542 ·Status: COMPLETED ·Phase: PHASE3
-
LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients
NCT04728932 ·Status: COMPLETED ·Phase: PHASE3
-
RandomIsed sTudy of Physiologic cArdiac stimuLation in patIents With Atrio-ventricular Conduction Disease
NCT07279870 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Left Bundle Branch Pacing Versus Conventional Pacing in Atrioventricular Block
NCT05129098 ·Status: COMPLETED ·Phase: NA
-
RCT Study of Levosimendan Improving Prognosis of Cardiac Arrest
NCT05956431 ·Status: UNKNOWN ·Phase: PHASE4
-
Levosimendan Efficacy for Veno-arterial ECMO Weaning: a Retrospective Study
NCT03346824 ·Status: UNKNOWN
-
Comparison of Oxygen Interventions and Defibrillator Efficiency
NCT02317029 ·Status: TERMINATED ·Phase: NA
-
Time-dependent Amiodarone Treatment in Atrial Fibrillation
NCT03432663 ·Status: COMPLETED ·Phase: PHASE4
-
Cardiac Autonomic Denervation for Cardio-inhibitory Syncope
NCT05572034 ·Status: UNKNOWN ·Phase: NA
-
REmote Cardiac MOnitoring of At-risk SYNCope Patients After Emergency Department Discharge -RCT
NCT05066347 ·Status: RECRUITING ·Phase: NA
-
Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
NCT04065893 ·Status: COMPLETED
-
Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients
NCT03221764 ·Status: COMPLETED ·Phase: PHASE2
-
Left Bundle Branch Area Pacing in Patients After TAVR
NCT05024279 ·Status: UNKNOWN ·Phase: NA
-
Postoperative Atrial Fibrillation Suppression By Nerve Stimulation
NCT03533140 ·Status: UNKNOWN ·Phase: NA
-
A Novel Patient Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
NCT03908346 ·Status: COMPLETED ·Phase: NA
-
Recurrent Ventricular Arrythmias in ICU
NCT07033065 ·Status: NOT_YET_RECRUITING
-
Left Bundle Branch Area Pacing in Heart Failure Patients With Ejection Fraction Below Normal
NCT06148571 ·Status: RECRUITING
-
Transcutaneous Carbon-dioxide Monitoring in Electrophysiological Procedures in Deep Sedation
NCT04038476 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Prophylactic Amiodarone for Shockable Cardiac Arrest
NCT04845607 ·Status: UNKNOWN ·Phase: PHASE3
-
Conduction System Stimulation to Avoid Left Ventricle Dysfunction
NCT06026683 ·Status: COMPLETED ·Phase: NA
-
Safety Profile of the Combination of Levosimendan and IV Beta Blocker in Cardiogenic Shock: a Retrospective Study
NCT04938375 ·Status: UNKNOWN
-
Amantadine to Speed Awakening After Cardiac Arrest
NCT02486211 ·Status: COMPLETED ·Phase: PHASE2