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Myocardial Mechanics in Athlete's Heart

NCT05543525 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 191

Last updated 2023-08-30

No results posted yet for this study

Summary

Echocardiographic assessment of the endurance athletes' heart remains challenging due to a phenotypic overlap between reactive physiological adaptation and pathological remodelling. The lower range of normal values of lLeft ventricle systolic ejection fraction (LVEF) and global longitudinal strain (GLS) in athletes makes it difficult to differentiate changes related to adaptive remodelling or indicative of early cardiomyopathy.

This study aims to improve the assessment of athletes' hearts by identifying echocardiographic phenotypes, using a speckle tracking including temporal deformation pattern and layer-specific approach, and to define predictive factors of subtle LV systolic dysfunction and of mechanical LV abnormalities.

Conditions

  • Athlete Heart

Interventions

OTHER

Echocardiography

Transthoracic echocardiography

OTHER

Cardiopulmonary exercise testing

Cardiopulmonary exercise testing

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV

  • INSERM, CIC 1433

    collaborator UNKNOWN

  • Central Hospital, Nancy, France

    lead OTHER

Principal Investigators

  • Nathalie Pace, MD · CHRU Nancy

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2022-01-01
Completion
2022-01-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05543525 on ClinicalTrials.gov