The SPOT-HPV Study
NCT05524025 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 360
Last updated 2026-01-21
Summary
The purpose of this research is to evaluate a new test for oral HPV DNA in saliva ('oral rinse test').
Conditions
- HPV Infection
- HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions
- DIAGNOSTIC_TEST
-
Salivary TTMV-HPV DNA Test
Mouthwash rinse
- DIAGNOSTIC_TEST
-
Blood TTMV-HPV DNA Test
Blood test
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Eleni M Rettig, MD · Brigham and Women's Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-11-30
- Primary Completion
- 2024-09-01
- Completion
- 2026-01-01
Countries
- United States
Study Locations
More Related Trials
-
The STOP-HPV Scale Up Study
NCT06831383 ·Status: RECRUITING ·Phase: NA
-
Zinc Sulfate for Human Papillomavirus (HPV)
NCT03404310 ·Status: TERMINATED ·Phase: NA
-
Carrageenan for the Prevention of Oral HPV Infection
NCT05746988 ·Status: UNKNOWN ·Phase: NA
-
Investigation Into the Infectivity Levels of Human Papilloma Virus (HPV) in Tonsillar Tissue
NCT02841631 ·Status: UNKNOWN
-
RTX-321 Monotherapy in Patients With HPV 16+ Tumors
NCT04672980 ·Status: TERMINATED ·Phase: PHASE1
-
Phase II Evaluation of AHCC for the Eradication of HPV Infections
NCT02405533 ·Status: COMPLETED ·Phase: NA
-
HUC-MSC for Treatment of High-risk HPV Infection
NCT06610773 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Pilot Study Comparing the Effectiveness of Campus Intervention to Increase HPV Vaccine Rate Among College Aged Men
NCT02508701 ·Status: TERMINATED ·Phase: NA
-
Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)
NCT05026138 ·Status: RECRUITING
-
Typing of Human Papilloma Virus (HPV) From Female Genital Warts
NCT01192282 ·Status: COMPLETED
-
A Study HB-201 in Patients With Newly Diagnosed HPV16+ Oropharynx or Locally Advanced Cervical Cancer
NCT04630353 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females
NCT05584332 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety Profiles of SR-T100 Gel on External Genital Warts/Condyloma Acuminate(EGWs)
NCT01796821 ·Status: COMPLETED ·Phase: PHASE2
-
Broad Spectrum HPV Vaccine Dose Escalation Study (V502-002)
NCT00851643 ·Status: COMPLETED ·Phase: PHASE1
-
Hespecta Vaccination in HPV+ Tumors or Malignant Lesions
NCT02821494 ·Status: COMPLETED ·Phase: PHASE1
-
Study of FluBHPVE6E7 in HPV-16 Infected Women
NCT04490512 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Study of HPV Therapeutic DNA Vaccine (NWRD08) in Patients With Cervical HPV16 and/or HPV18 Positive
NCT05905354 ·Status: UNKNOWN ·Phase: NA
-
Merck IIT: RRP Pembro and Lenvatinib
NCT04645602 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination
NCT03501992 ·Status: COMPLETED ·Phase: NA
-
"Facts Tell… and With Stories Sell?" Combining Viewer-tailored Personal Human Papillomavirus (HPV) Narrative Video With HPV Vaccine Information Video to Improve HPV Vaccine Uptake
NCT06587243 ·Status: RECRUITING ·Phase: NA
-
Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3)
NCT02354534 ·Status: COMPLETED ·Phase: PHASE1
-
SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma
NCT01676792 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis
NCT04724980 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Human Papillomavirus 6/11 in the Lower Airway of Neonates
NCT00549250 ·Status: COMPLETED
-
NWRD09 for HPV-16 Positive and HPV-16 Related Intraepithelial Neoplasia and Cervical Cancer Patients.
NCT06741150 ·Status: RECRUITING ·Phase: NA