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Investigation Into the Infectivity Levels of Human Papilloma Virus (HPV) in Tonsillar Tissue

NCT02841631 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2019-05-03

No results posted yet for this study

Summary

Human Papilloma Virus (HPV) has been shown to be a cause of Head \& Neck Squamous Cell Carcinoma (HNSCC) and the majority of current studies focus on what is happening in patients with a HPV HNSCC. But there is limited investigation into HPV infection in the oropharynx of patients who do not have HNSCC. The current incidence of oral HPV infection is not known in the general population locally and there is also limited information on what particular localities within the mouth that patients' harbour HPV infection what strains are present and if there are any differences in viral load.

Therefore the aim of this project is to investigate within patients that undergo tonsillectomies the rate of HPV infection in tonsils to determine the amount of HPV present within the community.

Conditions

  • Human Papillomavirus, Palatine Tonsil

Interventions

GENETIC

HPV status and typing of tissue

HPV status and typing of tissue

Sponsors & Collaborators

  • University of Derby

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-07-01
Primary Completion
2020-07-31
Completion
2020-10-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02841631 on ClinicalTrials.gov