Nitric Oxide Lung Diffusing Capacity in Systemic Sclerosis
NCT05505617 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 9
Last updated 2026-04-22
Summary
To date, two devices to measure nitric oxide lung diffusing capacity (DLNO) are commercially available in Europe. Previous research has shown systematic between-device differences in lung diffusing capacity outcomes in healthy people (Radtke et al. ERJ Open Res. 2021 Sep 13;7(3)). The extent and magnitude of between-device differences in people with lung function impairment and ventilation inhomogeneities is unknown.
Conditions
Interventions
- OTHER
-
Single-breath nitric oxide lung diffusing capacity measurements according to type of device in random order.
Device: Jaeger Masterscreen TM (PFT Pro, Vyaire, Hoechberg, Germany) Device: HypAir Medisoft (Medisoft, Dinant, Belgium)
Sponsors & Collaborators
-
University of Zurich
collaborator OTHER -
Holger Dressel
lead OTHER
Principal Investigators
-
Holger Dressel, Prof · University of Zurich
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-10-17
- Primary Completion
- 2025-05-01
- Completion
- 2026-03-01
Countries
- Switzerland
Study Locations
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