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Lung Diffusing Capacities Normality Thresholds in Pulmonary Fibrosis and Emphysema

NCT07091838 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2025-07-29

No results posted yet for this study

Summary

The investigators tested the usefulness of lung diffusing capacities for carbon monoxide (DLco) and nitric oxide (DLNO) normality thresholds of 5th and 2.5th percentiles for the assessment of intersitial pulmonary fibrosis (IPF) and pulmonary emphysema (PE). Computed tomography (CT) of the chest was taken as a gold standard for the presence of lung parenchymal abnormalities typical of these conditions. The investigators retrospectively utilized the DLco and DLNO data obtained by a single device in sixty-six subjects with IPF included in two previous studies and in fifty-four new subjects with PE, both documented by quantitative CT of the chest.

Conditions

  • Interstitial Pulmonary Fibrosis, Emphysema

Sponsors & Collaborators

  • IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-13
Primary Completion
2025-06-30
Completion
2025-07-07

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07091838 on ClinicalTrials.gov