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Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

NCT05504265 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 102

Last updated 2025-03-20

No results posted yet for this study

Summary

This study was designed to compare analgesic efficacy and safety of different perioperative analgesic modes in minimally invasive esophagectomy for esophageal cancer.

Conditions

  • Esophageal Cancer
  • Perioperative Analgesia
  • NSAIDs
  • Opioid
  • Patient-controlled Analgesia

Interventions

DRUG

Preemptive flurbiprofen axetil

50mg once，30min before induction anesthesia

DRUG

Postoperative flurbiprofen axetil

50mg bid

DEVICE

Patient-controlled analgesia pump

Sufentanil 2.5 μg/kg+ondansetron 8mg, prepared to 100ml normal saline; background dose: 2 ml/h, single press analgesic pump injection volume: 0.5 ml, locking time: 15 min.

Sponsors & Collaborators

  • Cancer Institute and Hospital, Chinese Academy of Medical Sciences

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-10
Primary Completion
2025-09-30
Completion
2025-12-20

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05504265 on ClinicalTrials.gov