Comparison of the Effects of Esketamine, Sufentanil, or Lidocaine on Tussis Reflection During Upper Gastroscopy

NCT05497492 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2023-10-10

No results posted yet for this study

Summary

the frequency of tussis, nausea and vomiting, and/or body movements observed at the insertion of the endoscope into the pharyngeal cavity or within 5 min of endoscope insertion.

Conditions

  • Anesthesia

Interventions

DRUG

propofol

single administration of propofol

DRUG

propofol and sufentanil

administration of propofol and sufentanil in combination

DRUG

propofol and esketamine

administration of propofol and esketamine in combination

DRUG

propofol and lidocaine

administration of propofol and lidocaine in combination

Sponsors & Collaborators

  • Beijing Tiantan Hospital

    collaborator OTHER
  • Beijing Friendship Hospital

    lead OTHER

Principal Investigators

  • Haijun Hou, MD · Beijing Friendship Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-11-05
Primary Completion
2023-12-30
Completion
2023-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05497492 on ClinicalTrials.gov