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Do "sugar Swings" Impact the Brain Function and the Eating Behaviors of People with Type 1 Diabetes

NCT05487534 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2024-10-09

No results posted yet for this study

Summary

In type 1 diabetes, it is common to choose the food we eat according to the blood sugar level and the insulin dose and vice versa. Beyond the nutritional aspects, the relationship to food and the resulting eating behaviors can be a source of suffering. Also, it has been reported that one out of two people over 60 years of age living with type 1 diabetes has cognitive impairment. Changes in cognitive functions can have important implications for daily well-being, diet (e.g., the ability to modulate cravings), and treatment decisions to manage diabetes.

One factor that can affect both eating behaviors and cognitive function is variation in blood glucose levels.

This research aims to better understand the impact of glycemic variability in disordered eating behaviors and cognitive impairment, and its consequences on self-management skills in people with type 1 diabetes.

The hypotheses are that i) higher glycemic variability is associated with higher disordered eating behaviors and poorer cognitive function in people with type 1 diabetes, and that differences exist between sexes, ii) higher disordered eating behaviors and poorer cognitive function are associated with lower self-management skills; and iii) cognitive impairment, interoception awareness and insulin resistance may mediate the relationship between glycemic variability and disordered eating behaviors.

This research study will contribute to highlighting the consequences of blood sugar fluctuations, "sugar swings", in daily life, in particular the way they disrupt eating behaviors and brain function. A better understanding of the mechanisms involved could eventually allow for early detection and management of these problems. Our study will also seek to understand the patients' point of view, which will allow the design of appropriate and meaningful recommendations.

Conditions

Interventions

OTHER

Observational

The same self-reported questionnaires and cognitive tests will be completed by both groups. There is no intervention.

Sponsors & Collaborators

  • CHU de Quebec-Universite Laval

    collaborator OTHER

  • Institut de Recherches Cliniques de Montreal

    collaborator OTHER

  • Centre d'expertise Poids, Image et Alimentation (CEPIA)

    collaborator UNKNOWN

  • Institut universitaire de cardiologie et de pneumologie de Québec, University Laval

    collaborator OTHER

  • Laval University

    lead OTHER

Principal Investigators

  • Sylvain Iceta, MD, PhD · Institut universitaire de cardiologie et de pneumologie de Québec, University Laval

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-26
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05487534 on ClinicalTrials.gov