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Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia

NCT05487196 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 88

Last updated 2025-04-27

Study results available
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Summary

The purpose of this randomized controlled trial is to compare the effectiveness of epidural clonidine, dexmedetomidine, or fentanyl adjuncts for labor analgesia.

Conditions

  • Pregnancy Related

Interventions

DRUG

Clonidine

Clonidine belongs to the drug classification of antihypertensives

DRUG

Dexmedetomidine

Dexmedetomidine belongs to the drug classification of sedatives

DRUG

Fentanyl

Fentanyl belongs to the drug classification of analgesic opioid agonists and is used as the standard of care

DRUG

Ropivacaine

Ropivacaine belongs to the drug classification of local or regional anesthesia for surgery and is used as standard of care

Sponsors & Collaborators

  • Grace Lim, MD, MS

    lead OTHER

Principal Investigators

  • Grace Lim, MD, MS · University of Pittsburgh

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-28
Primary Completion
2023-07-31
Completion
2023-07-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05487196 on ClinicalTrials.gov