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Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest

NCT05474170 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2026-04-03

Study results available
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Summary

The International Liaison Committee on Resuscitation regularly publishes a Consensus on Science with Treatment Recommendations but guidelines can nevertheless differ when knowledge gaps persist. In case of pediatric cardiac arrest, the American Heart Association recommends following the adult resuscitation sequence i.e., starting with chest compressions. Conversely, the European Resuscitation Council advocates the delivery of 5 initial rescue breaths before starting chest compressions. Carrying out a randomized trial in children in cardiac arrest to assess the impact of these strategies would prove particularly challenging and ethical concerns may prevent such a trial from being performed. This will be a superiority, cross-over randomized trial whose goal is to determine the impact of these 2 resuscitation sequences on alveolar ventilation in a pediatric model of cardiac arrest. While not definitive, its results could help fill part of the current knowledge gap.

Conditions

  • Cardiopulmonary Arrest
  • Pediatric ALL
  • Resuscitation

Interventions

OTHER

AHA resuscitation sequence

Starting the cardiopulmonary resuscitation by following the AHA guideline, meaning starting with 15 chest compressions, followed by 2 ventilations

OTHER

ERC resuscitation sequence

Starting the cardiopulmonary resuscitation by following the ERC guideline, meaning starting with 5 initial ventilations, then alternating 15 chest compressions with 2 ventilations

Sponsors & Collaborators

  • Service de la protection et de la sécurité, Neuchâtel

    collaborator UNKNOWN

  • École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care

    collaborator OTHER

  • University Hospital, Geneva

    collaborator OTHER

  • Geneve TEAM Ambulances

    lead OTHER

Principal Investigators

  • Laurent Suppan, MD · University of Geneva Hospitals and Faculty of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-01
Primary Completion
2022-09-01
Completion
2022-09-01

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05474170 on ClinicalTrials.gov