CLIC1 in Patients Presenting PD
NCT05446181 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 62
Last updated 2024-11-27
Summary
In this study, mononuclear cells, particularly monocytes, were collected from the peripheral blood of elderly patients who underwent orthopedic hip surgery under spinal anesthesia. We then observe the accumulation of chloride intracellular channel 1 (CLIC1), particularly the characteristic accumulation morphology and its function. The purpose of this study is to compare whether there is a difference in the degree and form of cytoplasmic CLIC1 accumulation between the elderly group with postoperative delirium (PD) and the elderly group without postoperative delirium. We'll also confirm whether this is appropriate as a predictor of postoperative delirium. In addition, we will establish a control group for the non-elderly group to check the difference due to aging itself.
Conditions
- Hip Fractures
- Hip Disease
Interventions
- BEHAVIORAL
-
Perioperative delirium
Perioperative delirium
- PROCEDURE
-
Hip surgery
Orthopedic hip joint surgery under spinal anesthesia
Sponsors & Collaborators
-
Seoul National University Bundang Hospital
lead OTHER
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-27
- Primary Completion
- 2024-10-30
- Completion
- 2024-10-30
Countries
- South Korea
Study Locations
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