CLIC1 in Patients Presenting PD

NCT05446181 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 62

Last updated 2024-11-27

No results posted yet for this study

Summary

In this study, mononuclear cells, particularly monocytes, were collected from the peripheral blood of elderly patients who underwent orthopedic hip surgery under spinal anesthesia. We then observe the accumulation of chloride intracellular channel 1 (CLIC1), particularly the characteristic accumulation morphology and its function. The purpose of this study is to compare whether there is a difference in the degree and form of cytoplasmic CLIC1 accumulation between the elderly group with postoperative delirium (PD) and the elderly group without postoperative delirium. We'll also confirm whether this is appropriate as a predictor of postoperative delirium. In addition, we will establish a control group for the non-elderly group to check the difference due to aging itself.

Conditions

  • Hip Fractures
  • Hip Disease

Interventions

BEHAVIORAL

Perioperative delirium

Perioperative delirium

PROCEDURE

Hip surgery

Orthopedic hip joint surgery under spinal anesthesia

Sponsors & Collaborators

  • Seoul National University Bundang Hospital

    lead OTHER

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-27
Primary Completion
2024-10-30
Completion
2024-10-30

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05446181 on ClinicalTrials.gov