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Physical Activity and Cognitive Function in Older Adults: A Novel Role for GPLD1

NCT04645134 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2022-11-16

No results posted yet for this study

Summary

The investigators are conducting a cross-sectional, observational study to investigate whether plasma GPLD1 concentrations are associated with higher cognitive function and better brain structure and function in two groups of older adults with high or low levels of physical activity.

Conditions

  • Aging
  • Cognitive Dysfunction

Interventions

BEHAVIORAL

Brain Health Assessments

The investigators are enrolling up to 28 healthy, older adults (ages 65-85 y, BMI 20-35 kg/m2) stratified by current physical activity level (equal inactive vs. equal highly active). Each physical activity group (inactive and highly active) will undergo a blood draw, body composition, resting metabolic rate, cognitive testing, and magnetic resonance (MR) imaging.

Sponsors & Collaborators

  • Pennington Biomedical Research Center

    lead OTHER

Principal Investigators

  • Kara L Marlatt, PhD, MPH · Pennington Biomedical Research Center

Eligibility

Min Age
65 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-04-01
Primary Completion
2022-03-17
Completion
2022-03-17

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04645134 on ClinicalTrials.gov