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Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease

NCT06684782 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 310

Last updated 2025-05-15

No results posted yet for this study

Summary

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by pathologic intraneuronal alpha-synuclein-positive Lewy bodies and neuronal cell loss. The cardinal clinical symptoms and signs of PD are bradykinesia, rigidity, tremor, postural instability, and freezing attacks. The prevalence of PD increases with age, affecting 1-2% of the population over the age of 65 years, and 3% of those over 85 years.

Restless legs syndrome (RLS) represents disturbing symptoms in lower limbs that lead to the urge to move, occurring in rest periods. Movements can partially or completely relieve these abnormal feelings. In 2014, the International RLS Study Group (IRLSSG) established five mandatory criteria for the diagnosis of RLS. Several studies supported that RLS and PD may share pathophysiological mechanisms.

Conditions

  • Restless Legs Syndrome

Interventions

OTHER

Screening for symptoms of restless leg syndrome

The patients will be screened for restless leg syndrome by clinical questioning.

Sponsors & Collaborators

  • Siriraj Hospital

    lead OTHER

Principal Investigators

  • Jindapa Srikajon, Doctor of Medicine · Siriraj Sleep Center, Faculty of Medicine, Siriraj Hospital, Mahidol University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2026-10-31
Completion
2026-11-30

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06684782 on ClinicalTrials.gov