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The Effect of Hypercapnia on Physiological Parameters During Short-term Breathing

NCT05441007 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2026-03-11

No results posted yet for this study

Summary

The aim of the project is to evaluate the effect of hypercapnia on physiological parameters in a healthy person during short-term hypoxia and hypercapnia.

Conditions

  • Hypoxia
  • Hypercapnia
  • Cardiac Output, High

Interventions

OTHER

Hypoxic

Hypoxic gas mixture Gas mixture of 10% O2 and 90% N2 for six minutes.

OTHER

Hypercapnic

Hypercapnic gas mixture Gas mixture of 21% O2, 5% CO2 74% N2 for six minutes.

OTHER

Hypoxic and Hypercapnic

Hypoxic and Hypercapnic gas mixture Gas mixture of 10% O2, 5% CO2 85% N2 for six minutes.

Sponsors & Collaborators

  • Czech Technical University in Prague

    lead OTHER

Principal Investigators

  • Karel Roubik, Professor · Czech Technical University in Prague

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-22
Primary Completion
2024-03-30
Completion
2024-06-30

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05441007 on ClinicalTrials.gov