Sex Differences in E-cig Perception: Study 1

NCT05432830 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2026-01-28

No results posted yet for this study

Summary

The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.

Conditions

  • Nicotine Addiction
  • E-Cig Use
  • Cigarette Smoking
  • Sex Differences

Interventions

OTHER

E-liquid Flavor 1

E-liquid containing 36mg/ml pronated nicotine will be administered with sweet e-cigarette flavor.

OTHER

E-liquid Flavor 2

E-liquid containing 36mg/ml pronated nicotine will be administered with cooling e-cigarette flavor.

OTHER

E-liquid Flavor 3

E-liquid containing 36mg/ml pronated nicotine will be administered with unflavored e-cigarette flavor.

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH
  • Yale University

    lead OTHER

Principal Investigators

  • Danielle Davis · Yale University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
44 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-04-30
Primary Completion
2025-07-18
Completion
2025-07-18

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05432830 on ClinicalTrials.gov