The Impact of Waterpipe Tobacco Flavors on Waterpipe Smoking Intentions, Perceptions, Patterns, and Toxicant Exposure

Summary

The overall aim of the current study is to determine if flavorings contribute to the initiation and maintenance of waterpipe (WP) smoking and also influence how a WP is smoked, which has implications for both risk of dependence but also smokers' level of exposure to tobacco-related toxicants. A total of 94 current WP smokers (47 low dependent, 47 high dependent) will be recruited. Based on our team's previous studies we conservatively assume a 20% attrition rate; thus, we will need to recruit 94 participants to have 76 complete all four sessions. Consistent with other laboratory studies of waterpipe smoking, participants who meet the following eligibility criteria will be asked to take part in the study.

Conditions

• Smoking, Hookah
• Waterpipe Smoking

Interventions

BEHAVIORAL

Flavored-Sweetened Waterpipe Tobacco

Pre-weighed flavored-sweetened waterpipe tobacco will be prepared.

BEHAVIORAL

Unflavored-sweetened waterpipe tobacco

Pre-weighed unflavored-sweetened waterpipe tobacco will be prepared.

BEHAVIORAL

Unflavored-very low sweetened waterpipe tobacco

Pre-weighed unflavored-very low sweetened waterpipe tobacco will be prepared.

BEHAVIORAL

Flavored-very low sweetened waterpipe

Pre-weighed flavored-very low sweetened waterpipe tobacco will be prepared.

Sponsors & Collaborators

• Virginia Commonwealth University

  collaborator OTHER

• American University of Beirut Medical Center

  collaborator OTHER

• National Institute on Drug Abuse (NIDA)

  collaborator NIH

• University of Oklahoma

  lead OTHER

Principal Investigators

• Theodore Wagener, PhD · University of Oklahoma

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

50 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2017-06-01

Primary Completion

2018-03-12

Completion

2018-03-12

Countries

• United States

Study Locations