Microbial Colonization of Oral Probiotics

Summary

The aim of this study is to evaluate the colonization efficacy of probiotic lozenges and powders containing specific prebiotics in healthy adults

Conditions

• Microbial Colonization

Interventions

DIETARY_SUPPLEMENT

Streptococcus salivarius K12 lozenge

In this study, a lozenge will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 lozenges containing prebiotic A

In this study, a lozenge containing a prebiotic will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 lozenges containing prebiotic B

In this study, a lozenge containing a prebiotic will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 lozenges containing prebiotics A and B

In this study, a lozenge containing two prebiotics will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 powder

In this study, a powder will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 powder containing prebiotic A

In this study, a powder containing a prebiotic will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 powder containing prebiotic B

In this study, a powder containing a prebiotic will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity

DIETARY_SUPPLEMENT

Probiotic S. salivarius K12 powder containing prebiotics A and B

In this study, a powder containing two prebiotics will be evaluated for its potential of delivering probiotic Streptococcus salivarius K12 to the oral cavity

DIETARY_SUPPLEMENT

Probiotic S. salivarius M18 lozenges

In this study, a lozenge containing will be evaluated for its potential of delivering probiotic Streptococcus salivarius M18 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius M18 lozenges containing prebiotic A

In this study, a lozenge containing a prebiotic will be evaluated for its potential of delivering probiotic Streptococcus salivarius M18 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius M18 lozenges containing prebiotic B

In this study, a lozenge containing a prebiotic will be evaluated for its potential of delivering probiotic Streptococcus salivarius M18 to the oral cavity.

DIETARY_SUPPLEMENT

Probiotic S. salivarius M18 + lozenges containing prebiotic A and B

In this study, a lozenge containing two prebiotics will be evaluated for its potential of delivering probiotic Streptococcus salivarius M18 to the oral cavity.

Sponsors & Collaborators

• BLIS Technologies Limited

  lead INDUSTRY

Principal Investigators

• John D Hale, PhD · Blis Technologies Ltd

• Rohit Jain, PhD · Blis Technologies Ltd, Dunedin, New Zealand

• John R Tagg, PhD · Blis Technologies Ltd, Dunedin, New Zealand

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-06-15

Primary Completion

2022-08-31

Completion

2022-09-15

Countries

• New Zealand

Study Locations