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Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota

NCT01473368 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 53

Last updated 2017-04-04

Study results available
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Summary

The purpose of this study is to compare and contrast the effects of the probiotic Saccharomyces boulardii, the antibiotic amoxicillin/clavulanate and the combination on the gut microbiota of healthy volunteers.

Conditions

  • Healthy Volunteers

Interventions

DIETARY_SUPPLEMENT

Saccharomyces boulardii

500 mg, 2 times daily for 14 days

DRUG

Amoxicillin Clavulanate

875/125 mg 2 times daily at least 1 hour before meals for 7 days

Sponsors & Collaborators

Principal Investigators

  • Ciaran P Kelly, MD · Beth Israel Deaconess Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2013-02-28
Completion
2013-02-28

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01473368 on ClinicalTrials.gov