Effects of CPAP on Visceral Fat Thickness
NCT01828281 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 141
Last updated 2015-11-16
Summary
We hypothesize that patients with untreated OSAS will have more visceral fat, fatty liver and increased carotid artery thickness whereas treatment with CPAP may reduce the mesenteric and liver fat, plasma lipids, carotid artery thickness.
Conditions
Interventions
- DEVICE
-
CPAP
All subjects will undergo ultrasound examination of the abdomen the day after overnight polysomnography (PSG) and then at 3 months after completion of therapeutic or subtherapeutic CPAP treatment of 4 cm water.
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Principal Investigators
-
Hui David, MD · Chinese University of Hong Kong
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-02-29
- Primary Completion
- 2013-10-31
- Completion
- 2015-08-31
Countries
- China
Study Locations
More Related Trials
-
Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients
NCT02127177 ·Status: COMPLETED ·Phase: NA
-
Effect of Continuous Positive Airway Pressure (CPAP) on Systemic Blood Pressure, Coagulability and Carotid Intima-media Thickness in Patients With Sleep Apnea
NCT00300599 ·Status: COMPLETED ·Phase: NA
-
Influence of Craniofacial Restriction on Rebound of Obstructive Sleep Apnea Following Weight Gain
NCT03051815 ·Status: COMPLETED
-
Obstructive Sleep Apnea (OSA), Oral Frailty, Dysphagia, Continuous Positive Airway Pressure (CPAP)
NCT05977296 ·Status: COMPLETED ·Phase: NA
-
The Effects of Obstructive Sleep Apnea and Its Intervention on Coronary Heart Disease
NCT02059993 ·Status: COMPLETED ·Phase: NA
-
Effect of Nasal Continuous Positive Airway Pressure (CPAP) Blood Pressure and Vascular Endothelial Growth Factor in Obstructive Sleep Apnea Syndrome
NCT00300872 ·Status: COMPLETED ·Phase: NA
-
Acute Effect of CPAP on Weight in Patients With Obstructive Sleep Apnea
NCT05253963 ·Status: COMPLETED ·Phase: NA
-
A Brief Lifestyle Modification Programme in Overweight Subjects With Obstructive Sleep Apnoea - Needs Assessment
NCT04262986 ·Status: UNKNOWN
-
Prevalence of OSAS in Chinese Elderly and Its CPAP Compliance
NCT02085720 ·Status: COMPLETED ·Phase: NA
-
Exploring the Role of Adipocyte Fatty Acid Binding Protein in the Association of Obstructive Sleep Apnea and Metabolic Dysfunction
NCT01173432 ·Status: COMPLETED ·Phase: NA
-
Early Signs of Atherosclerosis in Obstructive Sleep Apnea: Effects of Treatment
NCT00400543 ·Status: COMPLETED ·Phase: PHASE4
-
Fatty Liver and Obstructive Sleep Apnea
NCT00730873 ·Status: COMPLETED ·Phase: NA
-
The Effects of Treating Obese and Lean Patients With Sleep Apnea
NCT01578031 ·Status: COMPLETED ·Phase: NA
-
Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis
NCT00152711 ·Status: UNKNOWN ·Phase: NA
-
Effect of CPAP on Biomarkers in Patients With OSA
NCT01138865 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Fat Metabolism in OSA and COPD
NCT02157844 ·Status: COMPLETED
-
Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery
NCT01697878 ·Status: COMPLETED ·Phase: NA
-
Weight Gain After CPAP Treatment in Patients With Obstructive Sleep Apnea
NCT03567317 ·Status: COMPLETED ·Phase: NA
-
Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography
NCT05351515 ·Status: UNKNOWN
-
Markers in Exhaled Breath Condensate in Obstructive Sleep Apnoea (OSA) Patients
NCT00287638 ·Status: COMPLETED ·Phase: NA
-
Sleep Apnea Video Education for CPAP (SAVE-CPAP)
NCT02553694 ·Status: COMPLETED ·Phase: NA
-
Long Term Efficacy of Education Programme on Continuous Positive Airway Pressure Treatment
NCT01428921 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Simple Continuous Positive Airway Pressure on Patients With Obstructive Sleep Apnea
NCT03782844 ·Status: COMPLETED ·Phase: NA
-
The Endothelium Dysfunction in Patients of Obstructive Sleep Apnea Syndrome
NCT01699126 ·Status: COMPLETED ·Phase: PHASE4
-
Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea
NCT04061226 ·Status: COMPLETED