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Patient Derived Preclinical Models

NCT05324553 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2025-05-02

No results posted yet for this study

Summary

Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models.

This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.

Conditions

Interventions

PROCEDURE

Tissue Collection

Research tissue specimen will be obtained during the patient's clinical biopsy or clinical tumor resection, if feasible.

DIAGNOSTIC_TEST

Blood Collection

Up to 50 mL of research blood will be drawn around the time of the procedure. Additional blood may be collected in selected cases, as warranted, to monitor disease recurrence/remission or perform additional

DIAGNOSTIC_TEST

Buccal Swab

Buccal swab may be requested, if necessary, to generate germline data.

Sponsors & Collaborators

Principal Investigators

  • Aaron S. Mansfield, M.D. · Mayo Clinic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-06
Primary Completion
2027-03-31
Completion
2028-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05324553 on ClinicalTrials.gov