Social Determinants and a Diabetes Prevention Program Tailored for African Americans

Summary

African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based intervention that significantly delays or prevents Type 2 diabetes through the promotion of diet change, exercise and modest weight loss. However, weight loss from the DPP among AAs is about half that of White participants, and suboptimal AA attendance is a critical contributor. The investigators propose to conduct a study that will address social determinants (SD) that challenge DPP attendance with underserved African Americans from a safety net hospital. The investigators will examine DPP attendance and weight loss with participants randomized to 3 groups: standard DPP, a culturally-tailored DPP to address acceptability, and a culturally-tailored DPP enhanced to address socioeconomic-related barriers to DPP participation. This novel study is the first to tailor the DPP to address SD cultural and socioeconomic barriers that limit DPP attendance and reduce its effectiveness on outcomes. The proposed multidimensional, SD tailored DPP has great potential to be a feasible and scalable model to reduce DM risks among urban, African Americans and ultimately reduce DM disparities.

Conditions

• PreDiabetes
• Overweight and Obesity

Interventions

BEHAVIORAL

Culturally Tailored Diabetes Prevention Program

This intervention includes a culturally tailored DPP curriculum, class procedures, and handouts

BEHAVIORAL

Culturally Tailored DPP Enhanced with Socioeconomic Supports

This intervention includes the culturally tailored DPP curriculum, class procedures, and handouts along with promotional items for class participation, opportunities to attend class in-person or virtually through a digital platform, and assistance from a community health worker to provide linkage to health care services and community resources

BEHAVIORAL

Diabetes Prevention Program

This is the CDC TD2 evidence-based Diabetes Prevention Program

Sponsors & Collaborators

• University of Massachusetts, Amherst

  collaborator OTHER

• University of Kansas

  collaborator OTHER

• Children's Mercy Hospital Kansas City

  collaborator OTHER

• University Health

  collaborator UNKNOWN

• University of Missouri, Kansas City

  lead OTHER

Principal Investigators

• Jannette Y Berkley-Patton, PhD · University of Missouri-Columbia

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-07-20

Primary Completion

2025-12-31

Completion

2026-02-28

Countries

• United States

Study Locations